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KMID : 0391119930020010034
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Ulsan University Medical Journal
1993 Volume.2 No. 1 p.34 ~ p.38
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The Comparison of Platelet Indices between Normal Pregnancy and Severe Preeclampsia
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이인식
민원기/박용범/한지수/정동근/김암/지현숙/목정은
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Abstract
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The purpose of this retrospecitive study was to define platelet indices in severe preeclampsia(N=98) and to compare them to normal nonpregnant values(N=93) during the years 1990-1993 in the Department of Obstetrics and Gynecology, College of
medicine,
University of Ulsan, Asan Medical Center. Indices evaluated included platelet, count, mean platelet volume, and platelet distribution width. Mean platelet volume was not statistically different between two groups, however mean platelet count was
significantly decreased(p=0.029) and platelet distribution width was significantly increased(p=0.0001) and platelet distribution width was significantly increased (p=0.0001) in severe preeclampria. Mean platelet volume versus platelet count in
normal
pregnancy showed a significant inverse nonlinear relationship(r=-0.39, 9<0.0001) and that in preeclampsia was congruent with normal nonpregnant values. With same mean platelet volume, platelet distribution width showed tendency to shift to right
in
severe preeclampsia. These findings support the concept of severe preeclampsia as a compensated state of increased platelet comsumption comparing with normal pregnancy. We concluded from above results that quantification of platelet indices may
have
some value in screening for and following severe preeclampsia.
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KEYWORD
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